Perform selective photogenetic stimulation on neurons in indirect pathways that control steering, an
Published:
2023-08-04

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Perform selective photogenetic stimulation on neurons in indirect pathways that control steering, and analyze the activity of neurons during the steering process


A) Four A2A+DLS neurons from a representative mouse, wearing {product name} during free activity, were subjected to selective photogenetic activation and calcium imaging recording; B) Photogenetic stimulation causes animal circled behavior, and all data is aligned to the starting time point of circled behavior; C) A total of 354 neurons were recorded during the turning process; D) The calcium fluorescence signals of four representative neurons during the turning process are obtained through Δ F/F and normalization processing. Image excerpt: Jinyong Zhang et al., All optical imaging and patterned simulation with a one shot endoscope


对控制转向的间接通路中的神经元进行选择性光遗传刺激,分析神经元在转向过程的活动情况


A)来自一只代表性小鼠的4个A2A+ DLS神经元,小鼠在自由活动期间佩戴{产品名}进行选择性光遗传激活和钙成像记录;B) 光遗传刺激引起动物转圈行为,所有数据对齐至转圈行为起始时间点;C)转向过程所记录到的共354个神经元;D)4个代表性神经元在转向过程中的钙荧光信号,数据经过ΔF/F和归一化处理。图片摘自:Jinyong Zhang等人,All-optical imaging and patterned stimulation with a one-photon endoscope